Magnésio, Envelhecimento e Longevidade

Magnésio, Envelhecimento e Longevidade

 

REGIÕES DE SOLO RICO EM MAGNÉSIO E LONGEVIDADE

No Brasil, o solo é em geral, pobre em Magnésio, assim como as águas de abastecimento urbano, a as águas minerais, cujo teor dificilmente supera os 30 mg/litro, cifra que corresponde ao efeito cardioprotetor.

No Estado de Tocantins, em Arrais e Campos Belos, cidades edificadas em áreas de calcário dolomítico, rico em Magnésio, a água é muito dura e desagradável ao paladar, todavia, é usada pela população local e pelo gado, cuja vitalidade é reconhecida nos municípios vizinhos. Há também muitos casos de longevidade na população; estudos preliminares que deverão ser complementados com dados epidemiológicos que poderão elucidar a correlação com Magnésio.

Estudos semelhantes em outras regiões do país ricas em Magnésio poderão estabelecer a analogia com a tribo dos Hunza, do Paquistão, legendária pela sua longevidade, cujo hábito tradicional é a ingestão de um “leite glacial”, solução aquosa de minerais obtidos de rochas de alto teor de Magnésio, cuja ação sobre o organismo parece ter efeito prolongado, conferindo-lhe vigor físico e saúde e longevidade.

TEORIAS SOBRE O ENVELHECIMENTO E A SUA CORRELAÇÃO COM O  MAGNÉSIO

Dentre as inúmeras teorias que pretendem explicar o mecanismo do envelhecimento, incluindo o relógio biológico, a ligação cruzada do colágeno, erros da bio-síntese protéica, destaca-se uma teoria muito sedutora proposta pela escola francesa.

LABORIT evidencia o envelhecimento celular através da reação do organismo às condições do seu meio ambiente. Considerando que os nucleotídeos cíclicos AMPc e GMPc intervêm na transcrição do genoma, processo em que o AMPc facilita a diferenciação celular e o GMPc favorece a divisão, é evidente uma correlação com o Magnésio.

Ambos os nuclotídeos são controlados pela adenilato-ciclase, que é magnésio-dependente e está submetido à influencia dos hormônios e dos neuro – hormônios.

A reação simpático – adrenérgica bloquearia a divisão celular por intermédio do AMPc e facilitaria a diferenciação celular no curso do envelhecimento.

O Magnésio é tanto essencial ao êxito de ação simpático – suprarenal ao mesmo tempo que exerce múltiplas regulações hormonais e neuro – hormonais.

Na qualidade de “segundo mensageiro”, o magnésio atua ao nível subcelular e celular em inúmeras atividades no campo hormonal.

É interessante a hipótese de que a maior biodisponibilidade de Magnésio possa influenciar o genoma e consequentemente a vitalidade e longevidade de um grupo humano, como tem sido observado no ritmo de envelhecimento de várias regiões do mundo.

A pesquisa corrente tem evidenciado o papel crucial do Magnésio como inibidor da excitotoxicidade induzida pelo Ca++ através do canal NMDA, onde tem importância o glutamato, um neurotransmissor essencial ao processo de aprendizagem, gerador de circuitos neuroniais.

Com o declínio da melatonina, após a fase reprodutiva do organismo, instala-se uma fase de desequilíbrio em relação ao glutamato, fase essa associada à geração descompensada do radical hidroxila levando à destruição progressiva das redes neuroniais, sobretudo do hipotálamo.

Estas perdas neuroniais, amplamente estudadas em laboratórios, são correlacionadas com as doenças legadas ao envelhecimento: diabetes, doença de Parkinson, câncer, doenças cardíacas, etc. O magnésio e a melatonina partilham da ação antiexcitoxicidade neuronial e morte neuronial exercida pelo cálcio e pelo glutamato, desenvolvendo assim uma manifesta ação antienvelhecimento.

Arnoldo Velloso da Costa

Texto completo:

Parte 1: Magnésio e o Envelhecimento

Parte 2: O Magnésio e o Envelhecimento – EXIGÊNCIA NUTRICIONAL

Parte 3: Magnésio e Envelhecimento – INTERAÇÕES COM OUTROS NUTRIENTES

Parte 4: Magnésio e Envelhecimento – CONSIDERAÇÕES GERONTOLÓGICAS SOBRE O MAGNÉSIO

Parte 5: Magnésio e Envelhecimento – O COLÁGENO E A TENDÊNCIA À FIBROSE

Parte 6: Magnésio e Envelhecimento e Longevidade

Atenção: o sugerido é o Cloreto de Magnésio P.A. (para análise), em sais.

Leia mais acerca dos benefícios do Cloreto de Magnésio clicando AQUI

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